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#Actualsamoth

Posted 04 March 2013 - 06:35 AM

Well, newborns aren't fully developed, might as well be that kid didn't have CD4 expressing cells yet, or only few of them. So, have those few cells infected and die, and antiviral treatment in place to catch 'em before new cells are generated... why not. Can you tell? I can't.

Another possibility is that the assessment was not correct. The article doesn't tell what they did to verify that the baby doesn't have HIV. Did they do a PCR on antigen? Hopefully, because if they do the "normal" antibody tests, the big surprise could simply be that babies do not express antibodies to antigens they encounter early in their lives. If they did, no baby would ever be born, because both mother and baby would die from a graft-vs-host reaction (a baby is in some way an alien body!). So maybe the baby does have HIV, just no antibodies. More info would be needed to rule that out.

In any case, I don't deem this story entirely impossible, but it's probably not groundbreaking news. Much like that story a few years back when someone had a radical leukaemia treatment which basically killed every white blood cell in his body. Following that they gave him stem cells or donor blood or whatever, and later they saw HIV was gone. Surprise.

Of course, if you have a parasite (say a leech) stuck to your finger, and you cut off the entire arm, the parasite is gone.

#3samoth

Posted 04 March 2013 - 06:34 AM

Well, newborns aren't fully developed, might as well be that kid didn't have CD4 expressing cells yet, or only few of them. So, have those few cells infected and die, and antiviral treatment in place to catch 'em before new cells are generated... why not. Can you tell? I can't.

Another possibility is that the assessment was not correct. The article doesn't tell what they did to verify that the baby doesn't have HIV. Did they do a PCR on antigen? Hopefully, because if they do the "normal" antibody tests, the big surprise could simply that babies do not express antibodies to antigens they encounter early in their lives. If they did, no baby would ever be born, because both mother and baby would die from a graft-vs-host reaction (a baby is in some way an alien body!).

In any case, I don't deem this story entirely impossible, but it's probably not groundbreaking news. Much like that story a few years back when someone had a radical leukaemia treatment which basically killed every white blood cell in his body. Following that they gave him stem cells or donor blood or whatever, and later they saw HIV was gone. Surprise.

Of course, if you have a parasite (say a leech) stuck to your finger, and you cut off the entire arm, the parasite is gone.

#2samoth

Posted 04 March 2013 - 06:28 AM

Well, newborns aren't fully developed, might as well be that kid didn't have CD4 expressing cells yet, or only few of them. So, have those few cells infected and die, and antiviral treatment in place to catch 'em before new cells are generated... why not. Can you tell? I can't.

In any case, I don't deem this story entirely impossible, but it's probably not groundbreaking news. Much like that story a few years back when someone had a radical leukaemia treatment which basically killed every white blood cell in his body. Following that they gave him stem cells or donor blood or whatever, and later they saw HIV was gone. Surprise.

Of course, if you have a parasite (say a leech) stuck to your finger, and you cut off the entire arm, the parasite is gone.

#1samoth

Posted 04 March 2013 - 06:28 AM

Well, newborns aren't fully developed, might as well be that kid didn't have CD4 expressing cells yet, or only few of them. So, have those few cells infected and die, and antiviral treatment in place to catch 'em before new cells are generated... why not. Can you tell? I can't. In any case, I don't deem this story entirely impossible, but it's probably not groundbreaking news. Much like that story a few years back when someone had a radical leukaemia treatment which basically killed every white blood cell in his body. Following that they gave him stem cells or donor blood or whatever, and later they saw HIV was gone. Surprise. Of course, if you have a parasite (say a leech) stuck to your finger, and you cut off the entire arm, the parasite is gone.

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