Hodgman:
There's a BIG difference between gpu assembly (vendor specific and no public headers available) and hlsl assembly (cross vendor and public headers).
Would you rather that i replace "full control" with "Higher level of control" ? I agree in that case
What i meant is full control while remaining cross vendor.
I don't change my own shaders, i would probably not use this method to change my own shaders.

This method worked very well on DX9 and tested on many games ;) (Full game playthrough)

I wish i had a more reliable way as i had in DX9, but currently,
i don't see any other choice, and no one offered an alternative so far.

Nik02:
I only need to change Pixel shaders, so, while still remaining a challenge, it becomes a more feasible one imho.

It's very easy to say that something is impossible, i doubt that this is impossible, i've seen more complicated challenges completed and shipped.
I estimate that as challenging as it is, a single person well skilled in reversing and familiar with 3d APIs concepts can finish it in around 6 months of fully dedicated work ;)