I am not sure what he means by that statement, it isn't true, the points do not need to be equidistant from one another. I'm not sure what you mean by a curve that doubles back on itself, but Catmull-Rom is local in that if you have multiple points on your spline, if you move the 4th point, it will not affect the curve anywhere but with the lines that are attached to that point. I'm not that familiar with legrange, but I'm guessing moving one point would require a recalculation of the entire curve?
(This has a nice interactive example: http://www.ibiblio.org/e-notes/Splines/cardinal.html)