I'm not sure if you intended to post in the Music forum, sounds more like a Breaking In Topic. Unless you were applying for a musician job and you did want to post here. Also, some background on your education and jobs would be helpful. I can relate to Kylotan's words on the harsh reality. My own harsh analogy is, each interview is like taking a college exam, where the "teacher" will only pass the top 5% who take it
I recently intereviewed to a (non-gaming) developer job in which they commonly used a framework I am not familiar with, but my knowledge of MVC and other frameworks/CMSes using the methodology would make me good at learning it quickly. They were accepting of that fact, and would provide ramp-up time. Unfortunately, and perhaps not surprisingly, they interviewed someone who did know the framework, and he was hired.
So although on-the-job training and ramp-up to get working with the tools the company uses is not an impossibility. But with competition that can bypass that, it becomes more and more improbable to get in that situation.
Honestly, the closest I've ever gotten to get into the games industry (even if it was just QA) fell short, for what to me a pretty dumb and disappointing one- I have no car and their location was out of my reach, so I could not plan an interview in person, much less travel every day to work there. I was in college at the time.