As I've been working on this sprite application I kind of wonder what kind of people would want it, and what would the responses be. I've been working on this application for a few months off and on, it's purpose is to create pretransformed animated sprites using vertex blocks. The application will allow you to create animations, as well as create frames with multiple frames in them. (say for example you want to create a glitter effect with multiple orbs and didn't want 50 animations of 1 orb. but 10 of 5 orbs)
It will also allow you to code animations using C (angelscript) and have generated frames. I'm hoping to release a rough version of it this month, so keep your fingers crossed.