For those developers that have already completed a game and determined that it is too big for online, the Allegorithmic geniuses have used their knowledge to create Substance Redux. This product takes existing textures and lets you compress them up to 50% smaller than the original BMPs and even smaller than what DDS can do. This provides a way to reduce the overall size of your game to online distribution to be even smaller without any overhead.
Substance Redux also includes a way to view before and after images of the textures and you can dial up or down the quality setting as needed. The product is scheduled to ship in April.