Well now I am on the trail of trying to disable Optimus... and it looks like it might not be possible on my Dell XPS 15Z. :\ I tried disabling my Intel Chip on my device manager, and that pretty much breaks everything. Resolution is dropped to 800x600 - and I'm guessing its not GPU accelerated.
Going to follow up with NVidia.. man its really going to suck if this a dead end for my machine, after all this work!
AFAIK, you cannot disable Optimus. Intel's GPU is the only way NVIDIA's GPU can communicate with a display.
Nsight (and PerfKit, as Nsight relies on it) really had a problem with Optimus, and probably it still has (I haven't tried the latest version yet).
Btw, you should know how to activate NVIDIA's GPU in your application. :)
By default, Intel's GPU is used. Fortunately, it is so easy with Optimus.