It's a neat concept but very frustrating in application. I've read that Sony Online Entertainment's Wizardry Online has a feature just like that, but it's the kind of feature that promotes an extremely hardcore player base. Unless said items are easily retrievable and/or attainable, you can expect a game that'll attract a small niche of players who may stay a while. Anyone outside this niche are more likely to quit in a short amount of time. Implying that this is a multiplayer game we're discussing of course.