- Gender discrimination in the workplace
- Harassment and flat-out reprehensible behavior towards women in any venue
- Perceived lack of interest on the part of women in STEM fields
- Demographic bias in production of various entertainment media
Individually, the issues are all well within the realm of fixable. They only appear insurmountable when combined into a giant "oh noes evil men are destroying teh earths" fiasco.
The ironic thing is that the solution to each issue (and, indeed, the extent to which each issue is really a genuine problem) is unique to the issue itself, as are the causes and social inertia that perpetuate them. Attacked separately, none of those four things is all that difficult to fight.